The house is built against a green hill that overlooks a vast valley of acacia bush. It has easy access to the winding and wildlife-rich Palala River, offering boat cruises, catch and release fishing, and bird watching over the water. Day and nighttime game drives, as well as guided bush walks, allow guests to observe the flora and fauna of the area on the lowest level, teaching appreciation of the complexity of the Lapalala Wilderness ecosystem.

As a Lepogo Lodge, Melote House is committed to running sustainable tourism and supporting the environment it is a part of. Wildlife and habitat conservation is a priority for the house, and it actively participates in local conservation efforts to preserve the beautiful landscape. These efforts include supporting a cheetah breeding program, a pangolin conservation project, and a rhino sanctuary. Each program also gives back to local communities.